题目内容：

阅读下面短文，在空白处填入1个适当的单词或括号内单词的正确形式。

Sadness, feeling down and having a loss of interest or pleasure in daily activities 1. (be) symptoms familiar to all of us. But, if they affect our life substantially, they may be depression.

According to the Centers for Disease Control and Prevention (CDCP), 7.6 percent of people over the age of 12 have depression in any 2-week period, 2. shows the scale of the issue.

According to the World Health Organization (WHO), depression is the most common illness worldwide and the leading cause of 3. (disable). They estimate that 350 million people 4. (affect) by depression, globally.

5. (general), the symptoms include lack of joy and reduced interest in things. Depression is a mood disorder characterized by persistently (连续地) low mood and a feeling of sadness and loss of interest. It is a persistent problem, not a passing one, 6. (last) on average 6 to 8 months.

Diagnosis of depression starts 7. a consultation with a doctor or mental health specialist. It is important to seek help from a health professional to rule out different causes of depression, ensure an accurate diagnosis and secure safe and 8. (effect) treatment.

As for most visits to 9. doctor, there may be a physical examination 10. (check) physical causes and other conditions. Depression is a treatable mental disease.