题目内容：

    Jerome Karie and Isabella Lugoski met in their first physical chemistry class at the University of Michigan in 1940. Jerome Karie was in his first year of doctoral work, Isabella Lugoski was in her last year as an undergraduate(大学本科生), and they were laboratory partners. However, they didn't get along well at first.

Isabella Lugoski looked back on the past, “I walked into the physical chemistry laboratory and there's a young man in the desk next to mine with his equipment all set up running his experiment. I don't think I was very polite about my question. I asked him how he got there early and had everything all set up. He didn't like that. So we didn't talk to each other for a while.

Their relationship got going as they competed for the top grade in that course and they started to build connection because both of them were interested in chemistry. They married in 1942. By 1946, both of the Karies had earned doctorates in physical chemistry, and, after a period of time at the University of Chicago working on the Manhattan Project, moved to Washington DC to join the US Naval Research Laboratory.

Each specialized in a different aspect of X-ray crystallography(晶体学): Jerome focused on developing equations(方程式) that could determine how atoms(原子) were arranged inside complex molecules, while Isabella ran practical experiments to test how well the equations worked. Working together, they created what is now called the direct method for determining molecular structures(分子结构), which has allowed scientists to effectively study and copy complex organic molecules to continue further study.

Jerome Karie was awarded the Nobel Prize for Chemistry in 1985. Although he was disappointed that the Nobel committee had ignored Isabella's contribution to that work, she was unfazed. At that point, she had already won more awards and prize money for her experimental work than he had.

1.What did Isabella Lugoski do when she first met Jerome Karie?

A.She blamed him for his being late. B.She set up all his equipment for him.

C.She asked him a question impolitely. D.She observed his experiment silently.

2.What made Jerome Karie and Isabella Lugoski become connected?

A.Their common interest in chemistry. B.Their wonderful marriage since 1940.

C.Their pleasant first talk in a laboratory. D.Their successful cooperation in courses.

3.What is paragraph 4 mainly intended to show?

A.The Karies' encouraging further study. B.The Karies' good teamwork in science.

C.How the Karies worked with others. D.Why the Karies won the Nobel Prize.

4.Which of the following best explains “unfazed" underlined in the last paragraph?

A.Generous. B.Touched. C.Shocked. D.Calm.