题目内容：

Directions: After reading the passage below, fill in the blanks to make the passage coherent and grammatically correct. For the blanks with a given word, fill in each blank with the proper from of the given word; for the other blanks, use one word that best fits each blank.

Long-term low self-esteem can cause depression

Low self-esteem makes us feel bad about ourselves. But did you know that over time it also can cause the development of serious mental conditions such as depression?

Self-esteem is, very simply, the set of feelings you have about yourself. It’s developed by your experiences, thoughts, feelings, and relationships. 1. self-knowledge, which refers to how much you know about yourself, self-esteem is formed around whether you like yourself or not. Depression is much more than just feeling sad. It drains your energy and makes everyday activities difficult.

Doctors use low self-esteem as one possible symptom 2. they diagnose the mental condition of major depressive disorder. They don’t necessarily care 3. low self-esteem causes the depression or vice versa. However, personality researchers have long wondered about the chicken-and-egg problem of self-esteem and depression. Certainly, if you dislike yourself, you’ll be more likely  4. (depress). On the other hand, if you’re depressed, you’ll be more likely to feel bad about yourself. The only way that 5. (employ) to explore the highly related concepts of self-esteem and depression is through continuous research, 6. people are followed up over time.

A study on depression conducted by University of Basel researchers Julia Sowislo and Ulrich Orth, 7. (contrast) the competing directions of self-esteem to depression vs depression to self-esteem. The findings have revealed that over time low self-esteem is a risk factor for depression, regardless of who is tested and how. The study indicates that low self-esteem causes depression 8. not vice versa.

Therefore, if a person has low self-esteem, there’s a 9. (great) risk of developing depression. This is a very important discovery because it shows that 10. (improve) a person’s self-esteem can make him or her feel better.